Near infra-red 670nm increases ATP: recharging batteries in old eyes, Gkotsi et al. 2014
Near-infrared 670 nm light significantly increased ATP production in aging retinal tissue, providing quantitative evidence for mitochondrial recharging.
Low-level laser therapy maintains vision in retinitis pigmentosa over 7 years, Ivandic & Ivandic 2014
After four initial treatments of LLLT, visual acuity increased to 20/20 in each eye. Visual fields normalized except for a mid-peripheral absolute concentric scotoma. Five years after discontinuation of LLLT, a relapse was observed. LLLT was repeated (another four treatments) and restored the initial success.
670 nm vs 830 nm: optic nerve injury and retinal degeneration Giacci et al. 2014
This case report describes the effects of low-level laser therapy (LLLT) in retinitis pigmentosa (RP). 670 nm LED superior to 830 nm for retinal/optic nerve protection, reducing reactive oxygen species and oxidative DNA damage.
670 nm light reduces oxidative stress and preserves visual function after optic nerve injury, Szymanski et al., 2013
670 nm preserved 40% more retinal ganglion cells following optic nerve crush injury through enhanced mitochondrial function and reduced oxidative stress.
670 nm light boosts mitochondrial membrane potential and reduces retinal inflammation (Kokkinopoulos et al. 2013)
670 nm light increased mitochondrial membrane potential and reduced age-related retinal inflammation via metabolic enhancement.
670nm photobiomodulation as a novel protection against retinopathy of prematurity Natoli et al., 2013
670 nm reduced pathological neovascularization in oxygen-induced retinopathy models, offering novel preventive approach for retinopathy of prematurity.
670nm light protects cone photoreceptors from white light-induced degeneration. Albarracin & Valter et al. 2012
PBM preconditioning protected photoreceptors from light-induced damage, preserving structure and function through enhanced cellular resilience.
670nm Photobiomodulation in Inherited Retinal Degeneration, Gopalakrishnan S et al., 2012
670 nm preserved photoreceptor function and slowed degeneration in P23H retinitis pigmentosa model through mitochondrial redox state preservation.
Low-level laser therapy improves visual acuity in adolescent and adult patients with amblyopia, Ivandic et al., 2012
LLLT improved visual acuity 2-3 lines in adolescent and adult amblyopia patients, challenging conventional age-limited treatment windows with sustained effects.
670nm near-infrared light reduces oxidative stress and preserves vision after optic nerve injury, Fitzgerald et al. 2010
To our knowledge, this is the first demonstration that 670-nm NIR light can reduce oxidative stress and improve function in the CNS following traumatic injury in vivo.
