670nm PBM Therapy for Center-Involved Diabetic Macular Edema, Kim et al 2022
670 nm PBM reduced central subfield thickness 42 μm and improved visual acuity in center-involved diabetic macular edema.
670 nm PBM reduced central subfield thickness 42 μm and improved visual acuity in center-involved diabetic macular edema.
This pilot study aims to establish that treatment with near infrared light (NIR) reduces cystic macular oedema in patients with a retinal vein occlusion.
Red and near-infrared wavelengths (650–800 nm) were shown to activate cytochrome c oxidase (Complex IV), increase ATP production, and promote mitochondrial resilience. In ischemic RGC models, additional long-wavelength light exposure preserved mitochondrial function and improved cellular survival.
PBM preconditioning protected photoreceptors from light-induced damage, preserving structure and function through enhanced cellular resilience.