Low level laser therapy (LLLT/PBM) applications for treatment of corneal trauma, Koev et al. 2011
LLLT reduced corneal healing time 40% with superior clarity and reduced scarring versus standard care in traumatic corneal injury.
670nm near-infrared light reduces oxidative stress and preserves vision after optic nerve injury, Fitzgerald et al. 2010
To our knowledge, this is the first demonstration that 670-nm NIR light can reduce oxidative stress and improve function in the CNS following traumatic injury in vivo.
Blue light induces oxidative stress and autophagy leading to RPE cell death, Cheng 2021
Age-related macular degeneration (AMD) is the progressive degeneration of the retinal pigment epithelium (RPE), retina, and choriocapillaris among elderly individuals and is the leading cause of blindness worldwide.
Low level laser (PBM) therapeutic applications for treatment of acute iridocyclitis. Koev et al. 2010
LLLT (PBM) therapy accelerated inflammation resolution and reduced complications in acute iridocyclitis versus standard treatment alone.
Infrared low-intensity laser therapy improves orbital blood flow and slows myopia progression in children, Shurygina & Khadzhieva 2009
This work was designed to study the effect of low-intensity infrared laser radiation (LIIRR) on orbital circulation in children with progressive progressive short-handedness.
Neuroprotective effects of (670nm) near-infrared light in an in vivo model of mitochondrial optic neuropathy. Rojas et al. 2008
670 nm treatment preserved retinal ganglion cells and visual function in mitochondrial optic neuropathy model through enhanced mitochondrial enzyme activity.
Laser therapy resolves botulinum toxin–induced bilateral eyelid ptosis, Majlesi et al. 2008
The widespread use of botulinum toxin type A (BTX-A) for aesthetic procedures in recent years has brought about some unwanted side effects that, though they are self-limited, cause inconvenience for patients.
Near-infrared laser irradiation increases central retinal artery blood flow in humans Mii et al., 2007
Near-infrared irradiation of carotid artery and stellate ganglion increased central retinal artery blood flow without systemic changes in healthy volunteers.
Five-year follow-up of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD) K Koev et al 2018
Five-year follow-up showed sustained visual improvements and slowed AMD progression with LLLT, confirming long-term safety without adverse effects.
670nm photobiomodulation rescues retinal function, Eells et al., 2003
Landmark study: 670 nm LED rescued retinal function from methanol toxicity up to 50 hours post-intoxication, first linking in vitro mitochondrial effects to in vivo retinoprotection.
