Condition focus: Dry Eye Disease & Meibomian Gland Dysfunction (MGD):
Primary outcomes included change in tear breakup time, self-reported patient satisfaction, and adverse events. Physician-judged improvement in dry eye tear breakup time was found for 68 of 78 patients (87%) with seven treatment visits and four maintenance visits on average (medians), and 93% of patients reported post-treatment satisfaction with degree of dry eye syndrome symptoms. Adverse events, most typically redness or swelling, were found for 13% of patients. No serious adverse events were found.
Conclusions: Although preliminary, study results of intense-pulsed-light therapy treatment for dry eye syndrome caused by meibomian gland dysfunction are promising. A multisite clinical trial with a larger sample, treatment comparison groups, and randomized controlled trials is currently underway.
WaveFront Alignment: protocols differ, this study supports the broader rationale for light-based approaches to MGD. The Spectral WaveFront uses 670 nm and 810 nm in an ocular-specific geometry designed to support mitochondrial and inflammatory pathways relevant to eyelid and ocular-surface physiology.
Link to original research here
Editor’s note: For PBM wavelengths relevant to eyelid and ocular surface metabolism, see our WaveFront Evidence Alignment. Complementary human data on PBM safety and tear-film improvement are reported in Park 2022 and Antwi 2024. Mechanistic support for oxidative and inflammatory modulation is discussed in Begum 2013 and Goo 2023.
Related Articles
- Review: Intense Pulse Light (IPL) Treatment of Ocular Rosacea – Shergill 2024
- Meibomian Gland Dysfunction: PBM and Intense Pulsed Light Therapy as Rescue Treatment – Solomos 2021
- Low-Level Light Therapy (PBM) in Individuals with Dry Eye Disease – Antwi 2024
- Anti-Inflammatory Effect of Multi-Wavelength LED Irradiation – Goo 2023





